Projects

DNA replication is one of the major targets of cancer therapies, as cancer cells tend to proliferate faster than normal cells and are generally more prone to replication stress. Most of our current knowledge about DNA replication initiation, or origin firing, currently comes from model organisms, such as yeast, but their applicability to the human system is limited. It is important to study replication initiation in human cells in order to be able to exploit the findings in cancer therapies. The main objectives of this project are to identify novel players in various stages of human replication initiation and characterize the non-catalytic roles of DNA polymerase epsilon and protein Timeless in replisome assembly.

A collaborative and creative atmosphere in the learning process, professional feedback/feed forward, beliefs based on the university's values and systematic self-reflection contribute to achievement of the development goals of the teaching staff and students of Tallinn University of Technology. The aim of this study is to find out: How the lecturer introduces the subject; How the lecturer refers to the learning outcomes and evaluation criteria; Which teaching methods are mostly used by teachers of STEM subjects: What is the average percentage of active learning methods used per lesson; What do students think about the active learning techniques used in the learning process; What is the standard teaching material distributed to students, what teaching material do students prefer; What is the experience of students regarding the involvement in the learning process; What kind of a didactic support does the lecturer need and want the most; What kind of support or help do students need (and want) the most in the learning process; What is the practice of giving feed forward/feedback for teachers, what for students; What examples of good learning and teaching practice can be pointed out in comparison with the top 10 technical universities in the world